© Donald Weber/VII

Uzbekistan

Tuberculosis (TB) and HIV care continue to be the focus for MSF in Uzbekistan, which is among the 27 countries with the highest rates of multidrug-resistant TB.

Uzbekistan was once at the heart of the ancient Silk Road trade route connecting China with the Middle East and Rome.

In 1991, Central Asia’s most populous country emerged from more than 200 years of Russian rule as an independent state.

From 1989 to September 2016, the country had been ruled by President Islam Karmov.

Médecins Sans Frontières/Doctors Without Borders (MSF) has worked in Uzbekistan since 1997 and continues to work to improve the quality and availability of treatment for Tuberculosis (TB), which has high levels of the drug-resistant form of the disease.

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MSF’s work in Uzbekistan: 2017

TB programme

In January, MSF launched its clinical trial TB PRACTECAL in Nukus, Karakalpakstan, and had enrolled 55 patients by the end of 2017. The trial aims to evaluate regimens containing two promising new drugs, bedaquiline and pretomanid, combined with existing and repurposed drugs, over a much shorter course of six months. This treatment has the potential to be more effective and more tolerable, and does not require injections.

As part of the comprehensive TB care programme in Karakalpakstan, MSF works with the national and regional health ministries to implement models of care that are more patient-centred. In 2017, MSF supported the rollout of the new World Health Organization guidelines in 5 of 16 districts.





© Misha Friedman

 

During 2017, 2,466 patients started TB treatment; of these, 1,710 were treated for drug-sensitive TB and 756 for drug-resistant strains, including 79 for extensively drug-resistant TB (XDR-TB). Of the 756 drug-resistant TB patients, 130 were treated with new or repurposed drugs.

HIV care

Working with the health ministry at the Tashkent HIV project, MSF has set up a ‘one-stop shop’ facility to support the integration of services for HIV, TB, hepatitis C and provide more effective testing and treatment for co-infected patients. In 2017, MSF and the Republican AIDS Centre reached an agreement that MSF will test and treat high-risk groups, such as people who inject drugs and sex workers.

In 2017, 153 patients started treatment for hepatitis C and 14 patients were initiated on third-line antiretroviral (ARV) treatment for HIV, after their initial and subsequent regimens ceased to work. Almost 880 patients started first-line ARV treatment in 2017.

find out more in our international activity report >



 

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